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闽ICP备05005471号 厦门大学网站备案号 D200069
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报告人：顾正龙 教授
报告题目：Mitochondrial DNA Mutation and Disease: Young and Old
报告时间：2026年6月2日 16:00
报告地点：跃进楼学术报告厅
邀请人：罗周卿 教授
报告人简介：国际知名遗传学家，复旦大学特聘教授。1998年获得北京大学学士学位，2003年获得芝加哥大学博士学位。2006年于康奈尔大学任教，2018年晋升为终身正教授。获得多项NIH、NSF等资助，荣获华盛顿国际生命研究院 2011 年“营养学未来领袖”奖。在多种顶级国际学术期刊上发表文章逾60余篇，包括Nature、Nature Genetics、PNAS、Genome Research、FASEB、MBE、JBC等，引用总计超 4800次。
Mitochondria play important roles in development and health. Besides producing ATP, mitochondria are also responsible for a series of diverse cellular processes, including calcium signaling, iron homeostasis, steroid synthesis, heme biosynthesis, ROS production, and programmed cell death. Recently, mitochondria have also been implicated as master regulators for epigenetic and immune responses, partially through orchestrated communication between nuclear and mitochondrial genome. The importance of mtDNA mutation in diseases has been traditionally underappreciated due to multiple reasons, including technical difficulties and perceptive negligence. In this brief talk I will outline the logic underlying the importance of studying mtDNA in various diseases. Autism as an example for children diseases, will also be discussed.